Ruta graveolens as a potential source of neuroactive compounds to promote and restore neural functions

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Anti-tumour activity of Ruta graveolens extract.

An extract of Ruta graveolens was found to be cytotoxic to Dalton's lymphoma ascites (DLA), Ehrlich ascites carcinoma (EAC) and L929 cells in culture (IC100=16 mg/ml) and also to increase the lifespan of tumour bearing animals. The extract further decreased solid tumours developing from DLA and EAC cells when given simultaneously with elongation of the lifespan of tumour-bearing animals. A home...

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Algicidal and antifungal compounds from the roots of Ruta graveolens and synthesis of their analogs.

Bioassay-guided fractionation of the ethyl acetate extract of Ruta graveolens roots yielded rutacridone epoxide with potent selective algicidal activity towards the 2-methyl-isoborneol (MIB)-producing blue-green alga Oscillatoria perornata, with relatively little effect on the green alga Selenastrum capricornutum. The diol-analog of rutacridone epoxide, gravacridondiol, which was also present i...

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Clastogenic potential of Ruta graveolens extract and a homeopathic preparation in mouse bone marrow cells.

Ruta graveolens belonging to family Rutaceae has long been traditionally used as a medicinal plant as well as a flavoring agent in food. However, very little data are available on the toxicity of the plant. This report presents evidence on the genotoxic and clastogenic potential of an extract of Ruta graveolens and Ruta 200C, a homeopathic preparation. Various types of chromosomal aberrations w...

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Toxicity of Ruta graveolens Seeds’ Extracts on Male Wistar Rats

The multipurpose medicinal plant, Ruta graveolens, used widly as a traditional treatment for many diseases. The present study was carried out on Wistar rats to evaluate the toxicity of ethanolic and aqueous extracts of R. graveolens seeds at two different doses 50 and 200 mg/kg/day orally for 4 weeks. The rats were allotted to five groups, each of six rats. One group served as control. Two grou...

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Evaluation of thrombolytic potential of three medicinal plants available in Bangladesh, as a potent source of thrombolytic compounds

Objective: The present study is aimed to investigate in vitro thrombolytic activity of three Bangladeshi medicinal plants Averrhoa bilimbi (Oxalidiaceae), Clerodendrum viscosum (Verbanaceae) and Drynaria quercifolia (Polypodiaceae). Materials and methods: Each the plant was extracted with methanol at room temperature and the concentrated methanolic extracts (MEF) were fractionated by the modifi...

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ژورنال

عنوان ژورنال: Journal of Traditional and Complementary Medicine

سال: 2020

ISSN: 2225-4110

DOI: 10.1016/j.jtcme.2020.05.002